Links to abstracts of various studies available at PubMed that were beneficial in our research and may be useful to you. Additional information about the minerals and vitamins in On Task can be found here.
- Improvement of neurobehavioral disorders in children supplemented with magnesium-vitamin B6. I. Attention deficit hyperactivity disorders. “In almost all cases of ADHD, Mg-B6 regimen for at least two months significantly modified the clinical symptoms of the disease: namely, hyperactivity and hyperemotivity/aggressiveness were reduced, school attention was improved.”*
- Magnesium VitB6 intake reduces central nervous system hyperexcitability in children. “In all patients, symptoms of hyperexcitability (physical aggressivity, instability, scholar attention, hypertony, spasm, myoclony) were reduced after 1 to 6 months treatment.”*
- Assessment of magnesium levels in children with attention deficit hyperactivity disorder (ADHD). “Magnesium deficiency was found in 95 per cent of those examined”*
- The effects of magnesium physiological supplementation on hyperactivity in children with attention deficit hyperactivity disorder (ADHD). Positive response to magnesium oral loading test. “In the period of 6 months those examined regularly took magnesium preparations in a dose of about 200 mg/day…..In the group of children given 6 months of magnesium supplementation, independently of other mental disorders coexisting with hyperactivity, an increase in magnesium contents in hair and a significant decrease of hyperactivity of those examined has been achieved, compared to their clinical state before supplementation and compared to the control group which had not been treated with magnesium.”*
- [Effect of MAGNE-B6 on the clinical and biochemical manifestations of the syndrome of attention deficit and hyperactivity in children] “It was established that the administration of MAGNE-B6 led to improvements in the behavior, decreased the level of anxiety and aggression, improved both large- and small-scale mobility, decreased the level of synkinesis, increased the characteristics of attention, corrected the magnesium homeostasis, and favored normalization of the blood electrolytes. Reliable differences (p < 0.01 or 0.001) between the test and control groups in the degree of expression of the indicated disorders were observed.”*
- [The effect of deficiency of selected bioelements on hyperactivity in children with certain specified mental disorders] “The findings herein presented indicate that it is necessary to take into consideration a possible bioelements deficiency among children with ADHD. Consequently, the accomplished study proves that there is a need of magnesium supplementation in ADHD children irrespectively of other mental disorders.”*
- [The role of zinc in the treatment of hyperactivity disorder in children] “The dose of zinc sulfate used was 55 mg/day, which is equivalent to 15 mg zinc. The improvement achieved in ADHD children with the use of zinc sulfate appears to confirm the role of zinc deficiency in the etiopathogenesis of ADHD.”*
- Double-blind, placebo-controlled study of zinc sulfate in the treatment of attention deficit hyperactivity disorder. “Zinc monotherapy was significantly superior to placebo in reducing symptoms of hyperactivity, impulsivity and impaired socialization in patients with ADHD.”*
- Serum zinc correlates with parent- and teacher- rated inattention in children with attention-deficit/hyperactivity disorder. “These findings add to accumulating evidence for a possible role of zinc in ADHD, even for middle-class Americans, and, for the first time, suggest a special relationship to inattentive symptoms.”*
- Effects of zinc and ferritin levels on parent and teacher reported symptom scores in attention deficit hyperactivity disorder. “Results indicated that both low zinc and ferritin levels were associated with higher hyperactivity symptoms. Zinc level was also associated with anxiety and conduct problems. Since both zinc and iron are associated with dopamine metabolism, it can be speculated that low zinc and iron levels might be associated with more significant impairment in dopaminergic transmission in subjects with ADHD.”*
- The central role of magnesium deficiency in Tourette’s syndrome: causal relationships between magnesium deficiency, altered biochemical pathways and symptoms relating to Tourette’s syndrome and several reported comorbid conditions.*
- New therapeutic approach to Tourette Syndrome in children based on a randomized placebo-controlled double-blind phase IV study of the effectiveness and safety of magnesium and vitamin B6.*
- Association between magnesium intake and depression and anxiety in community-dwelling adults: the Hordaland Health Study*
- [Depression-like and anxiety-related behaviour of rats fed with magnesium-deficient diet]*
- A synergistic effect of a daily supplement for 1 month of 200 mg magnesium plus 50 mg vitamin B6 for the relief of anxiety-related premenstrual symptoms: a randomized, double-blind, crossover study.*
- Magnesium deficiency induces anxiety and HPA axis dysregulation: Modulation by therapeutic drug treatment.Magnesium deficiency induces anxiety and HPA axis dysregulation: Modulation by therapeutic drug treatment.*
- Behavioral characterization of A/J and C57BL/6J mice using a multidimensional test: association between blood plasma and brain-magnesium ion concentration with anxiety.*
- Prolonged treatment with vitamins C and E seperately and together decrease anxiety-related open-field behavior and acoustic startle in hooded rats.*
- Effect of magnesium chloride on psychomotor activity, emotional status, and acute behavioural responses to clonidine, d-amphetamine, arecoline, nicotine, apomorphine, and L-5-hydroxytryptohan.*
- Zinc sulfate as an adjunct to methylphenidate for the treatment of attention deficit hyperactivity disorder in children: a double blind and randomized trial [ISRCTN64132371].*
- Role of zinc in maternal and child mental health.*
- Improvement of neurobehavioral disorders in children supplemented with magnesium-vitamin B6. II. Pervasive developmental disorder-autism.*
- Magnesium profile in autism.*
- Nutrient supplementation approaches in the treatment of ADHD.*
- Zinc in attention-deficit/hyperactivity disorder.*
- Successful treatment of bipolar disorder II and ADHD with a micronutrient formula: a case study.*
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.